Ethylenediaminetetraacetic acid (EDTA) | Lab Tests Guide
Ethylenediaminetetraacetic acid (EDTA) | Lab Tests Guide
Nov 9, 2019
labtestsguide.com
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EDTA-induced pseudothrombocytopenia occurs when ethylenediaminetetraacetic acid (EDTA), an anticoagulant commonly used in blood collection tubes, triggers platelet clumping. EDTA binds to calcium ions, disrupting the balance needed to prevent platelet aggregation. As a result, platelets clump together, leading to an erroneously low platelet count in routine blood tests. To address this issue, alternative anticoagulants like citrate or heparin may be used. Additionally, warming the blood sample b
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