The Guardians claimed a surprising series win over Houston after entering the three-game set mired in a 10-game skid. The Astros dropped back-to-back home contests for the first time since suffering a three-game sweep to the San Francisco Giants in their first homestand of the year.

The Houston Astros look to bounce back against the Cleveland Guardians as Hunter Brown (9-3, 1.82 ERA) gets the start, his first since being named to the AL All-Star team. Left-hander Joey Cantilo (1-0, 3.41) pitches for Cleveland, which broke a 10-game losing streak with Monday's win in Houston.

The Astros will start Brandon Walter (1-1) against the Guardians and Slade Cecconi (3-4). Before watching this Astros vs. Guardians matchup, here's everything you need to know about Wednesday's action on the diamond,